Pharmacology

Diabetic ketoacidosis (DKA): Management

NIKAH "

  • Normal saline infusion (0.9%)
  • Insulin
  • K (potassium replacement)
  • Antibiotics (in case of infections)
  • H (bicarbonate infusion in severe acidosis)
Normal saline infusion is done to overcome extracellular fluid deficit. If plasma Na+ is more than 155 mmol/L, 0.45% NS can be given instead of 0.9% NS.
Intracellular fluid deficit is corrected with 5% or 10% dextrose.
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Methyl Dopa: Side effects

 

 "M.E.T.H.Y.L.D.O.P.A

  • Mental retardation
  • Electrolyte imbalance
  • Tolerence
  • Headache/Hepatotoxicity
  • psYchological upset
  • Lactation in female
  • Dry mouth
  • Oedema
  • Parkinsonism
  • Anemia (hemolytic)

 

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Valproate: Side effects

"V.A.L.P.R.O.A.T.E"

  • Vomiting
  • Alopecia
  • Liver toxicity
  • Pancreatitis/ Pancytopenia
  • Retention of fats (weight gain)
  • Oedema (peripheral oedema)
  • Anorexia
  • Tremor
  • Enzyme inhibition

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Antipsychotics: Uses

S.O.M.A.T.I.C "

 

  • Schizophrenia
  • Organic brain syndromes
  • Mania
  • Anxiety
  • Tetanus
  • Intractable cough
  • Control of vomiting
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