Hypokalemic Periodic Paralysis

Submitted by Nishanth_koda on Mon, 27/06/2011 - 00:08
in

Hypokalemic periodic paralysis (HPP) occurs in approximately 1 out of 100,000 people and is comparatively more common in asian men. HPP is to be considered in cases presenting with sudden onset of weakness. The paralytic attacks usually occur in the morning hours. 

Management: The treatment involves correction of Hypokalemia. An important aspect about i.v. administration of potassium (k+) is that it should not be administered in glucose containing fluids. Mannitol is the better medium. The reason being, glucose can drive more K+ into the cells worsening the hypokalemia and weakness. 

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Comments

Submitted by drpurushothaman on Tue, 28/06/2011 - 06:33.

Nishanth , after a long time today i logged in to this site. Seems highly informative.

About hypokalemic periodic paralysis , not so rare in our parts,This entity to be included in any sudden onlset weakness, age is important, not ussual in very young  children . ( less common ,but not impossible ). Attacks more in morning hours .

One important point in management is about the IV administration of Potasium during management of an attack , you should not give in glucose containing fluids. Better to give in mannitol . (More potasium enters to cells worsening the potasium level and worsens weakness. )

Submitted by Nishanth_koda on Tue, 28/06/2011 - 11:22.

I have added the details from your comment to the video. Will also add it on DQ Club.

Thank you Sir.

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