Drugs metabolized by acetylation

Submitted by Silverflame on Fri, 02/01/2009 - 21:05
in

' SHIP'

  • Sulfonamides including dapsone
  • Hydralazine
  • Isoniazid (INH)
  • Procainamide

4

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imageAcetylator polymorphism:Some individuals are slow acetylators and some are fast acetylators.The drugs metabolized by acetylation may become ineffective in fast acetylators and cause toxicity in slow acetylators.

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