General pharmacology

Therapeutic index: formula

'TILE':

TI = LD50 / ED50

2

Drugs with low Therapeutic index

'The Queen Likes to Dig Low'

  • Theophylline
  • Quinine
  • Lithium
  • Digoxin have

Low therapeutic index

0

G-proteins for receptors

"QISS & QIQ" (Kiss and Kick):
 
G-proteins and their respective receptors in alphabetical order:

  • G-protein Q: alpha 1 receptor,
  • G-proteins I: alpha 2 receptor ,
  • G-proteins S: beta 1 receptor ,
  • G-protein S: beta 2 receptor

&

  • G-protein Q: M1 receptor,
  • G-protein I: M2 receptor,
  • G-protein Q: M3 receptor.

4

Oral drugs forming insoluble complexes

' TIAPS

Read as “Tie-ups”.

  • Tetracycline with Iron compounds
  • Antacids/Phenytoin with Sucralfate

 

3
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